What is Diphenhydramine? Full information, usage, benefits and side effects

What is Diphenhydramine? Full information, usage, benefits and side effects


Diphenhydramine is an antihistamine that reduces the effects of the body's natural chemical histamine. Histamine can cause symptoms such as sneezing, itching, watery eyes, and a runny nose.


  • Diphenhydramine is used to treat sneezing, runny nose, watery eyes, hives, rashes, itching, and other cold and allergy symptoms.
  • Diphenhydramine is also used to treat motion sickness, induce sleep, and treat certain symptoms of Parkinson's disease.
  • Diphenhydramine may also be used for purposes not listed in this medication guide.


Diphenhydramine is available as tablets, fast-dissolving (dissolving) tablets, capsules, liquid-filled capsules, dissolving strips, powders, and oral liquids. When used to relieve symptoms of allergies, colds, and coughs, diphenhydramine is usually taken every 4-6 hours. When used to treat motion sickness, diphenhydramine is usually taken 30 minutes before departure and as needed before meals and before bed. When using diphenhydramine to treat insomnia, take it at bedtime (30 minutes before you plan to go to bed). When diphenhydramine is used to treat movement disorders, it is usually taken 3 times a day first, then he 4 times a day. Carefully follow directions on the package or prescription label, and ask your doctor or pharmacist for clarification on any part you do not understand.Take Diphenhydramine exactly as directed. Do not take more or less of it, or more often than your doctor's prescription or label indicates.

Side Effects:

Common side effects may include:

  • drowsiness
  • incoordination 
  • upset stomach


  • Please consult your doctor/physician/specialist before taking any healthcare products. In case of allergic reaction to the medicines/substance, please take immediate medical help.
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