What is Capreomycin  - Drug Information, Side Effects and Uses

What is Capreomycin - Drug Information, Side Effects and Uses

What is Capreomycin?

Capreomycin is an antibiotic medication that belongs to the class of drugs known as aminoglycosides. It is primarily used in the treatment of tuberculosis (TB) when other medications are not effective or when treating multidrug-resistant TB. Capreomycin works by inhibiting the growth of bacteria responsible for TB.

Uses:

Capreomycin is used for:

  1. Multidrug-Resistant Tuberculosis (MDR-TB): It is prescribed to treat tuberculosis caused by strains of Mycobacterium tuberculosis that are resistant to multiple other anti-TB medications.

  2. Extensively Drug-Resistant Tuberculosis (XDR-TB): Capreomycin may be used in the treatment of TB strains resistant to multiple first-line and second-line drugs.

Benefits:

  1. Treatment of Resistant TB: Capreomycin is effective against TB strains that do not respond to other commonly used anti-TB medications.

  2. Intramuscular Administration: It is often administered by intramuscular injection, ensuring its absorption and distribution in the body.

Side Effects:

Common side effects may include:

  • Nausea
  • Vomiting
  • Pain or irritation at the injection site
  • Hearing loss (especially at high doses or with prolonged use)

Serious side effects are uncommon but may include kidney problems or allergic reactions. Regular monitoring is essential to manage potential side effects.

Precautions:

  1. Kidney Disorders: Capreomycin should be used with caution in individuals Mwith pre-existing kidney problems.

  2. Hearing Impairment: Monitoring for hearing loss is crucial during treatment, especially at higher doses or with prolonged use.

  3. Pregnancy and Breastfeeding: Consultation with a healthcare provider is essential for pregnant or breastfeeding individuals.

Dosage:

The dosage of Capreomycin is determined by healthcare providers based on factors such as the type and severity of TB, the patient's weight, and kidney function.

General Dosage Guidelines:

  • Intramuscular Administration: The medication is typically administered by injection into the muscle.

Conclusion:

Capreomycin is a valuable medication in the treatment of drug-resistant forms of tuberculosis. Its use is carefully monitored due to potential side effects, and it is an essential component in the management of challenging TB cases.

References:

  1. U.S. National Library of Medicine. (2022). Capreomycin. medlineplus.gov/druginfo/meds/a682398.html

Author: Nikita Vishnoi BCA

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