What is Amlodipine; Benazepril? Full information, Usage, Benefits and Side effects

What is Amlodipine; Benazepril? Full information, Usage, Benefits and Side effects

Amlodipine; Benazepril is a combination medication that contains two active ingredients: amlodipine and benazepril. Amlodipine is a calcium channel blocker, while benazepril is an angiotensin-converting enzyme (ACE) inhibitor. This combination is used to treat high blood pressure (hypertension).

Usage:

  1. Hypertension: Amlodipine; Benazepril is prescribed for the treatment of hypertension, a condition characterized by elevated blood pressure.

How it Works:

  1. Amlodipine (Calcium Channel Blocker): Amlodipine relaxes blood vessels by blocking the influx of calcium into vascular smooth muscle cells. This results in vasodilation, reducing blood pressure.

  2. Benazepril (ACE Inhibitor): Benazepril inhibits the action of angiotensin-converting enzyme, which is involved in the production of angiotensin II—a substance that narrows blood vessels. By blocking this enzyme, benazepril helps blood vessels relax, further lowering blood pressure.

Benefits:

  1. Blood Pressure Control: The combination of amlodipine and benazepril helps control blood pressure by addressing different mechanisms involved in blood vessel regulation.

  2. Reduced Risk of Cardiovascular Events: Controlling hypertension can contribute to a reduced risk of cardiovascular events such as heart attacks and strokes.

Side Effects:

Common side effects may include:

  • Dizziness or lightheadedness
  • Swelling of the ankles or feet (peripheral edema)
  • Flushing
  • Cough (associated with ACE inhibitors)

Serious side effects are rare but may include:

  • Hypotension (very low blood pressure)
  • Changes in kidney function
  • Allergic reactions

Precautions:

  1. Kidney Function: Regular monitoring of kidney function is important, especially in individuals with pre-existing kidney conditions.

  2. Potassium Levels: Amlodipine; Benazepril may affect potassium levels. Avoid potassium supplements or high-potassium foods unless directed by a healthcare provider.

  3. Pregnancy and Breastfeeding: This combination is not recommended during pregnancy, and alternative medications may be considered. It is also not recommended during breastfeeding.

  4. Angioedema: ACE inhibitors, like benazepril, can rarely cause angioedema, a serious condition involving swelling of deeper layers of the skin.

Dosage:

The dosage of Amlodipine; Benazepril is determined based on the specific needs of the individual and their response to the medication. It is typically taken orally in the form of a tablet.

Conclusion:

Amlodipine; Benazepril is a combination medication that effectively addresses hypertension by combining the actions of a calcium channel blocker and an ACE inhibitor. It is important to use this medication under the guidance of a healthcare provider who can monitor blood pressure, assess side effects, and make dosage adjustments as needed. Regular follow-ups and adherence to the prescribed treatment plan contribute to the successful management of hypertension and the prevention of associated complications. Individuals should promptly report any unusual symptoms or side effects to their healthcare provider for proper evaluation and guidance.

Author: Nikita Vishnoi BCA

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