What is Isosorbide? Full information, usage, benefits and side effects

What is Isosorbide? Full information, usage, benefits and side effects


Isosorbide belongs to a class of drugs called vasodilators. It relaxes the blood vessels so the heart doesn't have to work as hard and needs less oxygen.


Isosorbide immediate release tablets are used to treat angina pectoris  [ Angina is a type of chest pain caused by reduced blood flow to the heart. Angina is a symptom of coronary artery disease. Angina is also called angina pectoris. Angina pain is often described as squeezing, pressure, heaviness, tightness or pain in the chest. ] in patients with coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Isosorbide extended-release tablets (long-acting) and extended-release capsules are used to treat chest pain in patients with coronary artery disease [ Coronary artery disease is caused by plaque buildup in the wall of the arteries that supply blood to the heart (called coronary arteries). Plaque is made up of cholesterol deposits. Plaque buildup causes the inside of the arteries to narrow over time. ]. Isosorbide can only be used to prevent angina. Not for use in the treatment of an episode of angina that has started.

Angina Pectoris


Coronary Artery Disease



Isosorbide is available as tablets, extended-release (long-acting) tablets, and oral extended-release capsules. Tablets are usually taken two to three times a day. The extended-release tablet is usually taken once a day in the morning. Sustained-release capsules are usually taken once daily.

Swallow the extended-release tablet or capsule whole. Do not crush, chew or break. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to clarify any areas you do not understand. Take isosorbide as directed. Do not take more or less, or more often than directed by your doctor.

Side Effects:

  • Signs of an allergic reaction, such as rashes; hives; itching; red, swollen, blistered, or peeling skin with or without fever. wheezing; tightness in the chest or throat; difficulty breathing, swallowing, or speaking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Mood swings, confusion, muscle pain or weakness, abnormal heartbeat, severe dizziness or fainting, fast heartbeat, increased thirst, seizures, feeling extremely tired or weak, not feeling hungry, unable to work, or Signs of fluid and electrolyte problems such as passing urine changes in urine output, dry mouth, dry eyes, or severe stomach upset or vomiting.
  • Difficulty breathing, slow breathing, or shallow breathing.
  • Upset stomach or vomiting.
  • diarrhea. 
  • headache.


Please consult your doctor/physician/specialist before taking any healthcare products. In case of allergic reaction to the medicines/substance, please take immediate medical help.


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