Ezetimibe is a medication used to lower cholesterol levels in the blood. It belongs to a class of drugs known as cholesterol absorption inhibitors. Ezetimibe is often prescribed in combination with statins to enhance the reduction of cholesterol. It works by inhibiting the absorption of cholesterol from the small intestine.
Uses of Ezetimibe:
Ezetimibe is primarily used for:
- Cholesterol Reduction: Lowering elevated levels of total cholesterol and low-density lipoprotein (LDL) cholesterol.
How Ezetimibe Works:
Ezetimibe acts on the brush border of the small intestine, preventing the absorption of cholesterol from food and bile. By reducing the amount of cholesterol absorbed, Ezetimibe helps lower overall cholesterol levels in the bloodstream.
Benefits of Ezetimibe:
- Cholesterol Management: Effectively lowers total cholesterol and LDL cholesterol.
- Cardiovascular Risk Reduction: May contribute to a decreased risk of cardiovascular events.
Dosage and Administration:
- Dosage varies based on cholesterol levels, individual response, and other factors.
- Ezetimibe is typically taken orally in the form of tablets, with or without food.
- Follow the prescribed dosage and instructions provided by healthcare professionals.
Side Effects of Ezetimibe:
While generally well-tolerated, Ezetimibe may cause side effects, including:
- Common effects: Diarrhea, abdominal pain, and fatigue.
- Less common effects: Elevated liver enzymes and allergic reactions.
- Report any severe or persistent side effects to a healthcare professional.
Precautions:
- Inform healthcare providers about existing medical conditions or medications.
- Use caution in individuals with a history of liver disease.
- Regular monitoring of liver function may be recommended.
Interactions:
- Ezetimibe may interact with certain medications, including cyclosporine and fibrates.
- Inform healthcare providers about all over-the-counter and prescription medications being taken.
Warnings:
- Liver function monitoring: Regularly assess liver function during treatment, especially in individuals at higher risk.
- Pregnancy and breastfeeding: Discuss the potential risks and benefits with a healthcare professional.
It's important to note that this information is general, and specific details can vary. Always consult with a healthcare professional for personalized advice before using Ezetimibe or any medication.
References:
- MedlinePlus - "Ezetimibe": medlineplus.gov/druginfo/meds/a603015.html
- Drugs.com - "Ezetimibe": www.drugs.com/ezetimibe.html
- RxList - "Ezetimibe": www.rxlist.com/zetia-drug.htm
Author: Nikita Vishnoi BCA
